This is a simple man-to-man offense that can be very effective if you have a good, athletic O4 who can shoot the shot from the free-throw line area, and also make a 1-on-1 dribble move to the hoop. Having good corner shooters makes it even more difficult to defend. This offense spreads the floor with good floor balance, and you can run a lot of options off of it. It is somewhat similar to the 4-out "High" offense.
You can use your high post player O4 as either a scorer or a screener. In diagram A, we pass the ball to O4 from the top. When the ball is at the top, there usually is no helpside defense and the X2 and X5 defenders may be wide from the basket. O4 can shoot the shot from the free-throw line, or make a 1-on-1 dribble move to the hoop. If either the X2 or X5 defender slide in to help (diagram B), O4 kicks the ball out to the short corner (where the help defense came from), for a wide-open shot. This is a killer if your O2 and O5 are good shooters.
In diagram G, O4 screens for O2. O2 comes around the screen for the pass from O1 and the shot. O4 rolls to the hoop after screening.
Diagrams H and I show how other plays can be run off this set. In diagram H, we run a simple weave-screen play. O1 dribbles at O2, hands the ball off and screens X2. O2 comes around the screen with the ball and the shot. Diagram I shows the counter to this play when the X2 defender overplays O2... now O2 back-cuts for the pass and lay-up.