This play starts with a 4-across, down low spread setup (Diagram A).
The guts of the play is with your two strong low post players who position themselves at each low block. It is a pick and seal play that is very simple, and amazingly effective. The ball-side low post (O4) sets a pick for the opposite low post (O5) and seals the defender for inside position. O5 cuts around the screen to the middle of the lane looking for the pass and the easy, point blank shot (see Diagram B).
Now, look at Diagram C... if O4's defender (X4) switches and picks up O5, then O4 should have inside position (if he/she sealed the X5 defender correctly), and should get the pass for the easy lay-in. O4 need not be concerned about the "3-seconds" call when positioning inside the lane, as the 3-second count does not begin until the ball is touched inbounds.
Meanwhile, your outside players are making their cuts. O2 (your good outside shooter) makes a V-cut out and cuts back to the corner, looking for the pass and the three-point shot. After your post players get a couple easy lay-ups, the defense will "sag" into the paint and then O2 should get some good opportunities. O1 makes a cut out to the top of the ball-side three-point circle, looking for a pass, and also acts as the one player back on defense.
After making the in-bounds pass, O3 either becomes a re-bounder (if the pass goes inside), or cuts out to the ball-side corner. If the in-bounds pass went out on top to O1, then O3 should cut quickly to the corner and look for the pass back from O1 and the potential three-point corner shot.